When most people think of hormones, they think of things like stress, sex, growth or thyroid hormones. But tucked deep in your digestive system are two lesser-known players that are rapidly gaining attention: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). Together, these two gut-derived messengers help regulate how your body responds to food, playing key roles in controlling appetite, energy, blood sugar, and fat storage.
At Evolv, we believe understanding your biology is the first step to optimizing it. So let’s take a closer look at what these two hormones actually do—and why they matter for your health.
GLP-1 and GIP are part of a group of hormones known as incretins. These hormones are secreted by the cells lining your small intestine in response to eating—especially when you consume carbohydrates or fats.
You can think of incretins as early warning signals. Before your food has even finished digesting, they’re already sending messages to the rest of your body about what’s coming, so your system can prepare to process, store, or burn the incoming energy.
GLP-1 is secreted from specific intestinal cells (called L-cells) within minutes after digested nutrients arrive. Once released, it acts on multiple organs and tissues:
- In the pancreas, it increases insulin secretion in a blood-glucose-dependent way, helping your body absorb and use sugar more efficiently.
- In the stomach, it slows down the rate of digestion, keeping you fuller for longer.
- In the brain, it activates satiety centers—reducing appetite and helping you stop eating sooner.
- In the liver, it may reduce the production of glucose, further stabilizing blood sugar levels.
GIP is released by K-cells in the upper small intestine and responds quickly to the presence of nutrients, especially glucose and fat.
- In the pancreas, GIP works alongside GLP-1 to increase insulin secretion, helping reduce post-meal blood sugar spikes.
- In fat tissue, GIP can influence how fat is stored and used for energy.
- In the bones and brain, emerging research suggests GIP may have additional roles in protecting bone density and supporting cognitive function.
GLP-1 and GIP aren’t just teammates, they’re synergistic. In healthy individuals, they work in parallel to create a smooth, coordinated metabolic response to food:
1. You eat a meal.
2. GLP-1 and GIP are released into the bloodstream.
3. Insulin increases, blood sugar stabilizes, digestion slows down.
4. You feel full, energized, and balanced, without crashes or cravings.
When this system works well, it’s barely noticeable. But when it doesn’t, due to things like insulin resistance, chronic stress, or ultra-processed foods, you may experience weight gain, cravings, fatigue, or blood sugar instability.
The better your incretin response, the easier it is to maintain healthy energy levels and manage weight. GLP-1 and GIP are two of the body’s most important regulatory tools, but modern diets and stressors can throw them off balance.
At Evolv, we believe the key to metabolic health isn’t about overriding your body. It’s about supporting the hormones and systems that were already designed to keep you healthy.
That’s why we focus on natural, biology-first solutions—like our proprietary peptide, EV1 Peptide—that are designed to work with your hormone pathways, not against them.
GLP-1 and GIP are part of your body’s deeply intelligent design. They help your brain, gut, and metabolism stay in constant communication. When they’re functioning well, health becomes easier. More intuitive. More natural.
So the next time you feel full after a nourishing meal or energized without a sugar crash, you can thank your incretins. And with the right support, you can help them do their job even better.
Understanding how GLP-1 and GIP work in the body sets the stage for how Evolv GLP-1 Biomimetic is such a powerful innovation in metabolic support. Evolv GLP-1 is a proprietary supplement that combines our novel EV1 peptide with the natural delivery power of yeast. This peptide is engineered to mimic the effects of both GLP-1 and GIP and works within the boundaries of nutritional supplementation. It binds to GLP-1 and GIP signals in the gut and brain, gently activating the body’s natural satiety and metabolic regulation pathways, just like the incretin hormones your own cells produce after a meal.*
Because the peptide is delivered using yeast biomass, similar to dried baker’s yeast, it remains structurally recognizable in the digestive tract. This means it can be taken orally, daily, and safely.
Evolv GLP-1 is not a stimulant. It doesn’t override your body’s natural systems. Instead, it supports them, helping you regain hunger control, stabilize energy, and optimize metabolic function with every dose.
This is metabolic support, reimagined. And it’s backed by science, powered by nature, and designed for daily life.
EVOLV GLP-1
GLP-1 BENEFITS
At Evolv, we believe the key to metabolic health isn’t about overriding your body. It’s about supporting the hormones and systems that were already designed to keep you healthy.
Studies
Before we ever launched a product, we put our innovation—EV1 Peptide—through rigorous testing and research. It’s not enough to make bold claims. We’re here to earn your trust with data, transparency, and results.
GLP-1 BENEFITS
If you’ve heard about GLP-1, chances are it was in the context of weight loss. What most people don’t realize is that GLP-1’s benefits go far beyond the number on the scale.
